Showing posts with label radiobiophotonics. Show all posts
Showing posts with label radiobiophotonics. Show all posts

Thursday, November 2, 2017

Pink City, Radiobiophotonics and Normal Tissue Toxicity- Firewall

 

Pink City, Radiobiophotonics and Normal Tissue Toxicity

 AOCPM- AMPICON 2017-  Mini-Symposia

Dr. Rao V. L. Papineni

 



Association of Medical Physicists of India (AMPI) and Asia Oceania Federation of Organizations for Medical Physics (AFOMP),  jointly hosts 17th Asia Oceania Congress of Medical Physics (AOCMP 2017) and 38th Annual Conference of Association of Medical Physicists of India (AMPICON 2017)  at SMS Medical College and Hospitals, Jaipur, “Pink City” from 4th to 7th November 2017.
The theme for the conference is “Advances in Medical Physics: shaping the future of modern healthcare“. 




In response to the invitation, I have organized two mini-symposia at the conference.
1. Radiobiophotonics 
2. Normal Tissue Toxicity- Firewall.


Mini Symposia  on novel emerging topics of Radiological Physics is designed by organizers as part of the conference. The symposiums obviously will cover topics of Radiation Biology, Quality Assurance (QA), Radiation Protection, TG reports, Radiomics of cancer, Molecular Imaging and advanced techniques in diagnostics and therapy.


Radiobiophotonics & Normal Tissue Toxicity.  
Symposium Coordinator & Speaker:  Dr. Rao V. L. Papineni 
Authors: Rao Papineni & Shahid Umar
University of Kansas Medical Center, PXI. Inc, and PACT & Health USA


Visualization via "light" coupled with "ionizing radiation" has made a profound impact both in understanding the disease mechanism and its treatment.  Rapid advances in photonics also aided in bridging the physics and medicine towards the new front in Cancer Radiation Therapy.  This Session brings to forefront "Radiobiophotonics" bringing to fold the rapidly growing fields pertaining to biophotonics in relation to radiobiology and Radiation Therapy.  These fields, Molecular Image Guided Radiation Therapy (MIGRT), X-Ray Luminescence,  Radiobioluminescence, Microscopy, Cherenkov Luminescence and it's role in microdosimetry, metastatic tumor phototherapy, activated nanodelivery and particle therapy beam tracking will be discussed.  The normal tissue toxicity assessment during radiation therapy or Nuclear Accidents using Radiobiophotonics will be elaborated.   Epithelial regeneration model will be used to describe the use of photonics in assessing Normal tissue injury and pharmacological intervention.  Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury. The intestinal stem cell (ISC) niche provides Wnt, Notch and epidermal growth factor (EGF) signals supporting Lgr5(+) crypt base columnar ISCs for normal epithelial maintenance.  Little is known about the regulation of the ISC compartment after tissue damage. Exposure to high doses of radiation triggers a number of potentially lethal effects. Among the most severe is the gastrointestinal (GI) toxicity syndrome caused by the destruction of the intestinal barrier, resulting in bacterial translocation, systemic bacteremia, sepsis and death.  The pathophysiological downstream events and the search of effective radioprotective agents by us will be highlighted.  Further this symposia will describe the significance of such radiation pharma interventions as effective emergency nuclear countermeasures not only for patients undergoing abdominal irradiation for GI malignancies but to promote survival and delay mortality for victims of radiation exposure and nuclear disasters.

Other faculty at AMPICON 2017:
 International Faculty
 National Faculty

Jaipur “Pink city of India is most celebrated city of legendary Rajputana, the land of Rajput valour, still retains its beauty and charm despite the process of modernization. It was founded in 1727 AD by one of the great rulers of Kachhawaha clan, the astronomer king Sawai Jai Singh II and still retains its splendid valor.  Jaipur is is the capital city of Rajasthan and Rajasthan is perhaps the most tribally diverse, artistically decorative and architecturally magnificent regal in India. It is the land of royalty with lavish forts and majestic palaces that are apt reminder of a rich and romantic past that speaks of heroism, honor and chivalry. 

 Look forward to meeting friends and Colleagues.   

Papineni Labs are Biomedical Research Labs in Honor of my Father Mr. Papineni Venkateswara Rao.



    "Molecular Imaging - Wisdom to See for Maladies to Flee"
                                                         
                                                                                   Dr. Rao V. L. Papineni






Dr. Rao V. L. Papineni
Professor (Adjunct- assistant)
University of Kansas Medical Center KUMC
USA
Dr. Rao V. L. Papineni is an Adjunct faculty member at University of Kansas Medical Center, and a molecular theragnostics scientist at PXI,  USA. He received his doctoral degree in Biochemistry from University of Hong Kong (British Terr). Dr. Papineni had his early education from University of Madras, where he earned his Bachelors and Master’s Degree. After ten years in Research and Faculty positions at University of Hong Kong and Baylor college of Medicine (USA), he joined Kodak/Carestream Health, USA.  Dr. Papineni has made several inventions and chaired scientific sessions in International Biomedical Meetings and serves on the editorial board of Nanotech and Experimental Pharmacology journals.  As a distinguished scientist, he initiated advanced research programs to study Inflammation and oncology utilizing molecular imaging and nanotechnology based molecular tools.  He recently identified and coined “Radiobioluminescence” a novel X-ray induced radiation phenomena that have immense potential in development of cancer therapeutic strategies.  His lab is instrumental in development of MIGRT  Molecular Image Guided Radiation Therapy technology and utilizing radiobiophotonics and MIGRT in Drug Discovery related to Cancer and radiation medicine.

Wednesday, November 2, 2016

Radiation Cancer Meet- Madras Medley

                 

Cancer Treatment and Normal Tissue protection-  A 7-day jamboree      

 by Dr. Rao Papineni

Surrender of The City of Madras 1746.jpg 

This event (painting) dated some 270 years ago, near the Adyar River, Madras (Current Chennai), India, literally changed the the World-Order, and silently changed the global power quotients that led to the current English-speaking countries domination.  Turning the the clock further down, 2-year short of three centuries ago, money from Madras gifted by Elihu Yale laid the solid foundations of the current United States of America (USA), via Yale University and its products.

Madras, my hometown has its other notoriety- it is one of the place that has the world's most natural background Radiation.
Is this silent dose a boon or bane... it is something being looked at.
As always, excited to head back to one of my 5 hometowns to Deliver an Invited Lecture at the International Conference on Radiation Therapy and Medicine.


The young scientists and students from across the world are going to have a good dose of the Madras Masala-  a mix of talk from oncologists, physicians, immunologists, radiation therapists, pharmacologists, radiobiologists, particle therapy, computational physicists, nano technologists, nuclear medicine, radiologists, space biologists, nuclear protection folks, etc.

As a part of the International Planning Committee for ICRB, really proud of the constellation of experts gathering.  IAEA, ICRP, NCI, NIAID, NIH, AIIMS, Ion Beam, NIRS, CERN, NIH, BARC, are part of the groups represented at the ICRB, IBIBAM and ICRP programs.


The main ICRB conference is followed by IBIBAM  Workshop 



          Joie de vivre

The 7-day meet under Madras natural background radiation umbrella will sure impact the future...  developing young minds, building scientific collaborations, advancing the science and medicine.

Look forward to the meeting and the friends.

Wishing the Organizers all the Best.